SkinCortex

Ingredient

Niacinamide

A vitamin B3 derivative associated with barrier support and anti-inflammatory effects.

Barrier / inflammation support axisClinical

Mechanism of action

Niacinamide is a precursor to NAD/NADP and is associated with ceramide production, reduced transepidermal water loss, and modulated inflammatory signaling.

It is commonly discussed alongside acne-related redness and barrier compromise.

Notes

  • Generally well-tolerated across skin types.
  • Often paired with other actives to soften their irritation profile.

Targets

Mechanism axes engaged