SkinCortex

Ingredient

Occlusives

Water-resistant agents (petrolatum, dimethicone, plant butters) that reduce TEWL.

Skin barrier axisReview

Mechanism of action

Occlusives form a film that reduces transepidermal water loss.

Petrolatum is among the most studied; many ingredients exhibit varying degrees of occlusion.

Targets

Mechanism axes engaged

StructureReview

Skin Barrier

Stratum corneum + lipid matrix that controls water loss and limits irritant entry.

PhysiologyReview

Transepidermal Water Loss

Water diffusing outward through the stratum corneum; rises when the barrier is disrupted.