SkinCortex

Mechanism

Irritation Sensitivity

Heightened reactivity to ordinarily-tolerated stimuli; common in compromised barrier states.

Review

What it is

When the barrier is compromised, ingredients and stimuli that are well-tolerated by intact skin can cross more readily and trigger inflammatory or sensory responses.

This is not allergy — it is a context-dependent reactivity that improves as the barrier recovers.

Why it matters

It explains why some users react to many products even without a true allergy.

Related

Related mechanisms

Ingredient axes

Ingredients that interact with this step